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Construction of Escherichia coli Mutant with Decreased Endotoxic Activity by Modifying Lipid A Structure

Escherichia coli BL21 (DE3) and its derivatives are widely used for the production of recombinant proteins, but these purified proteins are always contaminated with lipopolysaccharide (LPS). LPS is recognized by the toll-like receptor 4 and myeloid differentiation factor 2 complex of mammalian immun...

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Detalles Bibliográficos
Autores principales:	Liu, Qiong, Li, Yanyan, Zhao, Xinxin, Yang, Xue, Liu, Qing, Kong, Qingke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483635/ https://www.ncbi.nlm.nih.gov/pubmed/26023843 http://dx.doi.org/10.3390/md13063388

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