Cargando…
Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates
How neuropeptides in the primate spinal cord regulate itch and pain is largely unknown. Here we elucidate the sensory functions of spinal opioid-related peptides and gastrin-releasing peptide (GRP) in awake, behaving monkeys. Following intrathecal administration, β-endorphin (10–100 nmol) and GRP (1...
Autores principales: | Lee, Heeseung, Ko, Mei-Chuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483774/ https://www.ncbi.nlm.nih.gov/pubmed/26119696 http://dx.doi.org/10.1038/srep11676 |
Ejemplares similares
-
Physiological Function of Gastrin-Releasing Peptide and Neuromedin B Receptors in Regulating Itch Scratching Behavior in the Spinal Cord of Mice
por: Sukhtankar, Devki D., et al.
Publicado: (2013) -
Over-Expression of the Gastrin-Releasing Peptide in Cutaneous Nerve Fibers and its Receptor in Spinal Cord in Primates with Chronic Itch
por: Nattkemper, Leigh A., et al.
Publicado: (2013) -
How Gastrin-Releasing Peptide Opens the Spinal Gate for Itch
por: Pagani, Martina, et al.
Publicado: (2019) -
Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors
por: Barry, Devin M., et al.
Publicado: (2020) -
Spinal cord interneurons expressing the gastrin-releasing peptide receptor convey itch through VGLUT2-mediated signaling
por: Aresh, Bejan, et al.
Publicado: (2017)