Functional conservation of an ancestral Pellino protein in helminth species

The immune system of H. sapiens has innate signaling pathways that arose in ancestral species. This is exemplified by the discovery of the Toll-like receptor (TLR) pathway using free-living model organisms such as Drosophila melanogaster. The TLR pathway is ubiquitous and controls sensitivity to pat...

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Detalles Bibliográficos
Autores principales: Cluxton, Christopher D., Caffrey, Brian E., Kinsella, Gemma K., Moynagh, Paul N., Fares, Mario A., Fallon, Padraic G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484250/
https://www.ncbi.nlm.nih.gov/pubmed/26120048
http://dx.doi.org/10.1038/srep11687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484250/
https://www.ncbi.nlm.nih.gov/pubmed/26120048
http://dx.doi.org/10.1038/srep11687

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