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Functional conservation of an ancestral Pellino protein in helminth species
The immune system of H. sapiens has innate signaling pathways that arose in ancestral species. This is exemplified by the discovery of the Toll-like receptor (TLR) pathway using free-living model organisms such as Drosophila melanogaster. The TLR pathway is ubiquitous and controls sensitivity to pat...
Autores principales: | Cluxton, Christopher D., Caffrey, Brian E., Kinsella, Gemma K., Moynagh, Paul N., Fares, Mario A., Fallon, Padraic G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484250/ https://www.ncbi.nlm.nih.gov/pubmed/26120048 http://dx.doi.org/10.1038/srep11687 |
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