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Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus

The pathological hallmarks of Alzheimer’s disease (AD) include amyloid beta (Aβ) accumulation, neurofibrillary tangle formation, synaptic dysfunction and neuronal loss. In this study, we investigated the neuroprotection of novel osmotin, a plant protein extracted from Nicotiana tabacum that has been...

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Detalles Bibliográficos
Autores principales: Ali, Tahir, Yoon, Gwang Ho, Shah, Shahid Ali, Lee, Hae Young, Kim, Myeong Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484370/
https://www.ncbi.nlm.nih.gov/pubmed/26118757
http://dx.doi.org/10.1038/srep11708