Cargando…

PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is characteristically one of the most rapidly proliferating tumors which outgrows functional blood supply and results in regional oxygen deprivation. Overexpression of PIM1, a serine/threonine kinase, has been identified recently in human cancers. Knowledge on PIM1 in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leung, Carmen Oi-ning, Wong, Carmen Chak-lui, Fan, Dorothy Ngo-yin, Kai, Alan Ka-lun, Tung, Edmund Kwok-kwan, Xu, Iris Ming-jing, Ng, Irene Oi-lin, Lo, Regina Cheuk-lam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484426/ https://www.ncbi.nlm.nih.gov/pubmed/25834102

Ejemplares similares

Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling
por: Leung, Carmen Oi-Ning, et al.
Publicado: (2016)

Down‐regulation of TIMP2 by HIF‐1α/miR‐210/HIF‐3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma
por: Kai, Alan Ka‐Lun, et al.
Publicado: (2016)

Variation of stemness markers expression in tumor nodules from synchronous multi-focal hepatocellular carcinoma – an immunohistochemical study
por: Lo, Regina Cheuk-lam, et al.
Publicado: (2017)

Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/β-catenin pathway
por: Lo, Regina Cheuk-Lam, et al.
Publicado: (2018)

Switching of Pyruvate Kinase Isoform L to M2 Promotes Metabolic Reprogramming in Hepatocarcinogenesis
por: Wong, Carmen Chak-Lui, et al.
Publicado: (2014)

Deleted in Liver Cancer 2 (DLC2) Was Dispensable for Development and Its Deficiency Did Not Aggravate Hepatocarcinogenesis
por: Yau, Tai On, et al.
Publicado: (2009)

Transcriptional Repressive H3K9 and H3K27 Methylations Contribute to DNMT1-Mediated DNA Methylation Recovery
por: Wong, Chun-Ming, et al.
Publicado: (2011)

MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis
por: Wong, Chun-Ming, et al.
Publicado: (2015)

Correction: EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers
por: Au, Sandy Leung-Kuen, et al.
Publicado: (2014)

EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers
por: Au, Sandy Leung-Kuen, et al.
Publicado: (2013)

Upregulation of the Wnt Co-Receptor LRP6 Promotes Hepatocarcinogenesis and Enhances Cell Invasion
por: Tung, Edmund Kwok-Kwan, et al.
Publicado: (2012)

Deleted in Liver Cancer 1 (DLC1) Negatively Regulates Rho/ROCK/MLC Pathway in Hepatocellular Carcinoma
por: Wong, Carmen Chak-Lui, et al.
Publicado: (2008)

SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
por: Cui, Chun-Ping, et al.
Publicado: (2017)

Use of high flow nasal cannula oxygen therapy for patients infected with SARS-CoV-2 outside intensive care setting
por: Tong, Chak Kwan, et al.
Publicado: (2023)

Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma
por: Tsui, Yu-Man, et al.
Publicado: (2017)

RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma
por: Ma, Wei, et al.
Publicado: (2016)

Cost-effectiveness of Pembrolizumab as a Second-Line Therapy for Hepatocellular Carcinoma
por: Chiang, Chi-leung, et al.
Publicado: (2021)

Downregulation of PIM1 regulates glycolysis and suppresses tumor progression in gallbladder cancer
por: Xue, Chen, et al.
Publicado: (2018)

Bromodomain-containing protein BRPF1 is a therapeutic target for liver cancer
por: Cheng, Carol Lai-Hung, et al.
Publicado: (2021)

Molecular genetic study in hepatocellular carcinoma: microRNA deregulation in multistep hepatocarcinogenesis
por: Ng, Irene Oi-Lin
Publicado: (2012)

Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1
por: Zhang, Vanilla Xin, et al.
Publicado: (2021)

Cancer stemness in hepatocellular carcinoma: mechanisms and translational potential
por: Tsui, Yu-Man, et al.
Publicado: (2020)

Inhibition of CMTM4 Sensitizes Cholangiocarcinoma and Hepatocellular Carcinoma to T Cell–Mediated Antitumor Immunity Through PD‐L1
por: Chui, Noreen Nog‐Qin, et al.
Publicado: (2021)

Investigation of Functional Synergism of CENPF and FOXM1 Identifies POLD1 as Downstream Target in Hepatocellular Carcinoma
por: Ho, Daniel Wai-Hung, et al.
Publicado: (2022)

Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma
por: Ho, Daniel Wai-Hung, et al.
Publicado: (2021)

Pim-2 Modulates Aerobic Glycolysis and Energy Production during the Development of Colorectal Tumors
por: Zhang, Xue-hui, et al.
Publicado: (2015)

Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
por: Lu, Chao, et al.
Publicado: (2022)

Downregulation of PIM1 Regulates Glycolysis and Suppresses Tumor Progression in Gallbladder Cancer [Retraction]
Publicado: (2023)

Inflammation and stem markers association to PIM1/PIM2 kinase-induced tumors in breast and uterus
por: Jiménez-García, Manuel-Pedro, et al.
Publicado: (2017)

Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway
por: Kung-Chun Chiu, David, et al.
Publicado: (2019)

Demographic and Epidemiological Contributions to Recent Trends in Cancer Incidence in Hong Kong
por: Wong, Irene Oi Ling, et al.
Publicado: (2021)

Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC
por: Wei, Lai, et al.
Publicado: (2019)

The role of PIM1/PIM2 kinases in tumors of the male reproductive system
por: Jiménez-García, Manuel Pedro, et al.
Publicado: (2016)

Pim1 promotes cell proliferation and regulates glycolysis via interaction with MYC in ovarian cancer
por: Wu, Yong, et al.
Publicado: (2018)

Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer
por: Lu, Chao, et al.
Publicado: (2021)

Deregulation of Frizzled Receptors in Hepatocellular Carcinoma
por: Chan, Kristy Kwan-Shuen, et al.
Publicado: (2018)

miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression
por: Leong, Ka-Wai, et al.
Publicado: (2017)

Physcion increases the sensitivity of hepatocellular carcinoma to sorafenib through miRNA-370/PIM1 axis-regulated glycolysis
por: Pan, Xiao-Ping, et al.
Publicado: (2023)

Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
por: Chiu, David Kung-Chun, et al.
Publicado: (2017)

MAP9/ERCC3 signaling cascade: A new insight on understanding the chromosomal instability in hepatocellular carcinoma
por: Mok, Etienne Ho Kit, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4toic72appi1kk5hic5a12mhs4