MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1

miR-146a is a NF-κB induced microRNA that serves as a feedback regulator of this critical pathway. In mice, deficiency of miR-146a results in hematolymphoid cancer at advanced ages as a consequence of constitutive NF-κB activity. In this study, we queried whether the deficiency of miR-146a contribut...

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Detalles Bibliográficos
Autores principales: Contreras, Jorge R., Palanichamy, Jayanth Kumar, Tran, Tiffany M., Fernando, Thilini R., Rodriguez-Malave, Norma I., Goswami, Neha, Arboleda, Valerie A., Casero, David, Rao, Dinesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484436/
https://www.ncbi.nlm.nih.gov/pubmed/25906746

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