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E2F1 enhances glycolysis through suppressing Sirt6 transcription in cancer cells
The fast proliferation of cancer cells requires reprogramming of its energy metabolism with aerobic glycolysis as a major energy source. Sirt6, a class III histone deacetylase, has been shown to down regulate glycolysis by inhibiting the expression of several key glycolytic genes. Based on the publi...
Autores principales: | Wu, Minghui, Seto, Edward, Zhang, Jingsong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484454/ https://www.ncbi.nlm.nih.gov/pubmed/25816777 |
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