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Inhibition of β-Catenin signaling suppresses pancreatic tumor growth by disrupting nuclear β-Catenin/TCF-1 complex: Critical role of STAT-3

Aberrant activation of β-catenin/TCF signaling is related to the invasiveness of pancreatic cancer. In the present study, we evaluated the effect of capsaicin on β-catenin/TCF signaling. In a concentration and time-dependent study, we observed that capsaicin treatment inhibits the activation of dish...

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Detalles Bibliográficos
Autores principales: Pramanik, Kartick C., Fofaria, Neel M., Gupta, Parul, Ranjan, Alok, Kim, Sung-Hoon, Srivastava, Sanjay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484476/
https://www.ncbi.nlm.nih.gov/pubmed/25869100

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