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Agreement on the prescription of antimicrobial drugs
BACKGROUND: There is universal awareness of the difficulties faced by doctors when prescribing antimicrobials. METHODS: Over a six-month period patients hospitalized in the ICU and under treatment with antibiotics and/or antifungals were eligible to participate in the study. The data were assessed b...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484637/ https://www.ncbi.nlm.nih.gov/pubmed/26123222 http://dx.doi.org/10.1186/s12879-015-0992-y |
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author | Casaroto, Eduardo Marra, Alexandre R. Camargo, Thiago Zinsly Sampaio de Souza, Ana Rita Araújo de Almeida, Carlos Eduardo Saldanha Pedroti, Elizia Piassi Victor, Elivane da Silva dos Santos, Oscar Fernando Pavão Edmond, Michael B. Campos, Alexandre Holthausen |
author_facet | Casaroto, Eduardo Marra, Alexandre R. Camargo, Thiago Zinsly Sampaio de Souza, Ana Rita Araújo de Almeida, Carlos Eduardo Saldanha Pedroti, Elizia Piassi Victor, Elivane da Silva dos Santos, Oscar Fernando Pavão Edmond, Michael B. Campos, Alexandre Holthausen |
author_sort | Casaroto, Eduardo |
collection | PubMed |
description | BACKGROUND: There is universal awareness of the difficulties faced by doctors when prescribing antimicrobials. METHODS: Over a six-month period patients hospitalized in the ICU and under treatment with antibiotics and/or antifungals were eligible to participate in the study. The data were assessed by two infectious diseases specialists. Once completed, all case forms were sent independently to both evaluators (TZSC and ARM) by e-mail. Based on the data received, the evaluator completed a form automatically generated on the e-mail and returned it to the original mailbox for further analysis. We assessed the level of agreement between infectious disease specialists and the physicians directly responsible for the decision to begin antimicrobial therapy, as well as to assess the appropriateness of the regimen prescribed. RESULTS: Among the antimicrobial regimens prescribed to the 177 patients, 36 % were considered inappropriate by specialist #1 and 38 % were considered inappropriate by specialist #2. We found 78 % agreement by at least one of the infectious disease specialists with the prescribed antimicrobial regimen, and in 49 % of cases both specialists agreed with the prescribed regimen. Both disagreed with the prescribed regimen in 22 % of the cases and they disagreed between themselves in 29 % of the cases. CONCLUSION: This study highlights the difficulties in prescribing effective empirical antimicrobial therapy - they are of such magnitude that even two specialists in infectious diseases, well acquainted with our hospital’s resistance patterns and our patients’ profiles have considerable disagreement. |
format | Online Article Text |
id | pubmed-4484637 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-44846372015-06-30 Agreement on the prescription of antimicrobial drugs Casaroto, Eduardo Marra, Alexandre R. Camargo, Thiago Zinsly Sampaio de Souza, Ana Rita Araújo de Almeida, Carlos Eduardo Saldanha Pedroti, Elizia Piassi Victor, Elivane da Silva dos Santos, Oscar Fernando Pavão Edmond, Michael B. Campos, Alexandre Holthausen BMC Infect Dis Research Article BACKGROUND: There is universal awareness of the difficulties faced by doctors when prescribing antimicrobials. METHODS: Over a six-month period patients hospitalized in the ICU and under treatment with antibiotics and/or antifungals were eligible to participate in the study. The data were assessed by two infectious diseases specialists. Once completed, all case forms were sent independently to both evaluators (TZSC and ARM) by e-mail. Based on the data received, the evaluator completed a form automatically generated on the e-mail and returned it to the original mailbox for further analysis. We assessed the level of agreement between infectious disease specialists and the physicians directly responsible for the decision to begin antimicrobial therapy, as well as to assess the appropriateness of the regimen prescribed. RESULTS: Among the antimicrobial regimens prescribed to the 177 patients, 36 % were considered inappropriate by specialist #1 and 38 % were considered inappropriate by specialist #2. We found 78 % agreement by at least one of the infectious disease specialists with the prescribed antimicrobial regimen, and in 49 % of cases both specialists agreed with the prescribed regimen. Both disagreed with the prescribed regimen in 22 % of the cases and they disagreed between themselves in 29 % of the cases. CONCLUSION: This study highlights the difficulties in prescribing effective empirical antimicrobial therapy - they are of such magnitude that even two specialists in infectious diseases, well acquainted with our hospital’s resistance patterns and our patients’ profiles have considerable disagreement. BioMed Central 2015-06-30 /pmc/articles/PMC4484637/ /pubmed/26123222 http://dx.doi.org/10.1186/s12879-015-0992-y Text en © Casaroto et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Casaroto, Eduardo Marra, Alexandre R. Camargo, Thiago Zinsly Sampaio de Souza, Ana Rita Araújo de Almeida, Carlos Eduardo Saldanha Pedroti, Elizia Piassi Victor, Elivane da Silva dos Santos, Oscar Fernando Pavão Edmond, Michael B. Campos, Alexandre Holthausen Agreement on the prescription of antimicrobial drugs |
title | Agreement on the prescription of antimicrobial drugs |
title_full | Agreement on the prescription of antimicrobial drugs |
title_fullStr | Agreement on the prescription of antimicrobial drugs |
title_full_unstemmed | Agreement on the prescription of antimicrobial drugs |
title_short | Agreement on the prescription of antimicrobial drugs |
title_sort | agreement on the prescription of antimicrobial drugs |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484637/ https://www.ncbi.nlm.nih.gov/pubmed/26123222 http://dx.doi.org/10.1186/s12879-015-0992-y |
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