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Design of a gelatin microparticle-containing self-microemulsifying formulation for enhanced oral bioavailability of dutasteride
In this study, a gelatin microparticle-containing self-microemulsifying formulation (SMF) was developed using a spray-drying method to enhance the oral delivery of the poorly water-soluble therapeutic dutasteride. The effect of the amount of gelatin and the type and amount of hydrophilic additives,...
Autores principales: | Baek, In-hwan, Ha, Eun-Sol, Yoo, Jin-Wook, Jung, Yunjin, Kim, Min-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484659/ https://www.ncbi.nlm.nih.gov/pubmed/26150696 http://dx.doi.org/10.2147/DDDT.S86458 |
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