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Optimization of a multi-well colorimetric assay to determine haem species in Plasmodium falciparum in the presence of anti-malarials

BACKGROUND: The activity of several well-known anti-malarials, including chloroquine (CQ), is attributed to their ability to inhibit the formation of haemozoin (Hz) in the malaria parasite. The formation of inert Hz, or malaria pigment, from toxic haem acquired from the host red blood cell of the pa...

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Detalles Bibliográficos
Autores principales:	Combrinck, Jill M., Fong, Kim Y., Gibhard, Liezl, Smith, Peter J., Wright, David W., Egan, Timothy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484700/ https://www.ncbi.nlm.nih.gov/pubmed/26099266 http://dx.doi.org/10.1186/s12936-015-0729-9

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