Rhein Elicits In Vitro Cytotoxicity in Primary Human Liver HL-7702 Cells by Inducing Apoptosis through Mitochondria-Mediated Pathway

Objective. To study rhein-induced apoptosis signaling pathway and to investigate its molecular mechanisms in primary human hepatic cells. Results. Cell viability of HL-7702 cells treated with rhein showed significant decrease in dose-dependent manner. Following rhein treatment (25 μM, 50 μM, and 100...

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Detalles Bibliográficos
Autores principales: Bounda, Guy-Armel, Zhou, Wang, Wang, Dan-dan, Yu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484835/
https://www.ncbi.nlm.nih.gov/pubmed/26221172
http://dx.doi.org/10.1155/2015/329831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484835/
https://www.ncbi.nlm.nih.gov/pubmed/26221172
http://dx.doi.org/10.1155/2015/329831

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