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Support system for pathologists and researchers

AIMS: In Japan, cancer is the most prevalent cause of death; the number of patients suffering from cancer is increasing. Hence, there is an increased burden on pathologists to make diagnoses. To reduce pathologists’ burden, researchers have developed methods of auto-pathological diagnosis. However,...

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Autores principales: Ishikawa, Takumi, Takahashi, Junko, Kasai, Mai, Shiina, Takayuki, Iijima, Yuka, Takemura, Hiroshi, Mizoguchi, Hiroshi, Kuwata, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485189/
https://www.ncbi.nlm.nih.gov/pubmed/26167378
http://dx.doi.org/10.4103/2153-3539.158911
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author Ishikawa, Takumi
Takahashi, Junko
Kasai, Mai
Shiina, Takayuki
Iijima, Yuka
Takemura, Hiroshi
Mizoguchi, Hiroshi
Kuwata, Takeshi
author_facet Ishikawa, Takumi
Takahashi, Junko
Kasai, Mai
Shiina, Takayuki
Iijima, Yuka
Takemura, Hiroshi
Mizoguchi, Hiroshi
Kuwata, Takeshi
author_sort Ishikawa, Takumi
collection PubMed
description AIMS: In Japan, cancer is the most prevalent cause of death; the number of patients suffering from cancer is increasing. Hence, there is an increased burden on pathologists to make diagnoses. To reduce pathologists’ burden, researchers have developed methods of auto-pathological diagnosis. However, virtual slides, which are created when glass slides are digitally scanned, saved in a unique format, and it is difficult for researchers to work on the virtual slides for developing their own image processing method. This paper presents the support system for pathologists and researchers who use auto-pathological diagnosis (P-SSD). Main purpose of P-SSD was to support both of pathologists and researchers. P-SSD consists of several sub-functions that make it easy not only for pathologists to screen pathological images, double-check their diagnoses, and reduce unimportant image data but also for researchers to develop and apply their original image-processing techniques to pathological images. METHODS: We originally developed P-SSD to support both pathologists and researchers developing auto-pathological diagnoses systems. Current version of P-SSD consists of five main functions as follows: (i) Loading virtual slides, (ii) making a supervised database, (iii) learning image features, (iv) detecting cancerous areas, (v) displaying results of detection. RESULTS: P-SSD reduces computer memory size random access memory utilization and the processing time required to divide the virtual slides into the smaller-size images compared with other similar software. The maximum observed reduction in computer memory size and reduction in processing time is 97% and 99.94%, respectively. CONCLUSIONS: Unlike other vendor-developed software, P-SSD has interoperability and is capable of handling virtual slides in several formats. Therefore, P-SSD can support both of pathologists and researchers, and has many potential applications in both pathological diagnosis and research area.
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spelling pubmed-44851892015-07-12 Support system for pathologists and researchers Ishikawa, Takumi Takahashi, Junko Kasai, Mai Shiina, Takayuki Iijima, Yuka Takemura, Hiroshi Mizoguchi, Hiroshi Kuwata, Takeshi J Pathol Inform Original Article AIMS: In Japan, cancer is the most prevalent cause of death; the number of patients suffering from cancer is increasing. Hence, there is an increased burden on pathologists to make diagnoses. To reduce pathologists’ burden, researchers have developed methods of auto-pathological diagnosis. However, virtual slides, which are created when glass slides are digitally scanned, saved in a unique format, and it is difficult for researchers to work on the virtual slides for developing their own image processing method. This paper presents the support system for pathologists and researchers who use auto-pathological diagnosis (P-SSD). Main purpose of P-SSD was to support both of pathologists and researchers. P-SSD consists of several sub-functions that make it easy not only for pathologists to screen pathological images, double-check their diagnoses, and reduce unimportant image data but also for researchers to develop and apply their original image-processing techniques to pathological images. METHODS: We originally developed P-SSD to support both pathologists and researchers developing auto-pathological diagnoses systems. Current version of P-SSD consists of five main functions as follows: (i) Loading virtual slides, (ii) making a supervised database, (iii) learning image features, (iv) detecting cancerous areas, (v) displaying results of detection. RESULTS: P-SSD reduces computer memory size random access memory utilization and the processing time required to divide the virtual slides into the smaller-size images compared with other similar software. The maximum observed reduction in computer memory size and reduction in processing time is 97% and 99.94%, respectively. CONCLUSIONS: Unlike other vendor-developed software, P-SSD has interoperability and is capable of handling virtual slides in several formats. Therefore, P-SSD can support both of pathologists and researchers, and has many potential applications in both pathological diagnosis and research area. Medknow Publications & Media Pvt Ltd 2015-06-23 /pmc/articles/PMC4485189/ /pubmed/26167378 http://dx.doi.org/10.4103/2153-3539.158911 Text en Copyright: © 2015 Ishikawa T. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Ishikawa, Takumi
Takahashi, Junko
Kasai, Mai
Shiina, Takayuki
Iijima, Yuka
Takemura, Hiroshi
Mizoguchi, Hiroshi
Kuwata, Takeshi
Support system for pathologists and researchers
title Support system for pathologists and researchers
title_full Support system for pathologists and researchers
title_fullStr Support system for pathologists and researchers
title_full_unstemmed Support system for pathologists and researchers
title_short Support system for pathologists and researchers
title_sort support system for pathologists and researchers
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485189/
https://www.ncbi.nlm.nih.gov/pubmed/26167378
http://dx.doi.org/10.4103/2153-3539.158911
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