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Support system for pathologists and researchers
AIMS: In Japan, cancer is the most prevalent cause of death; the number of patients suffering from cancer is increasing. Hence, there is an increased burden on pathologists to make diagnoses. To reduce pathologists’ burden, researchers have developed methods of auto-pathological diagnosis. However,...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485189/ https://www.ncbi.nlm.nih.gov/pubmed/26167378 http://dx.doi.org/10.4103/2153-3539.158911 |
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author | Ishikawa, Takumi Takahashi, Junko Kasai, Mai Shiina, Takayuki Iijima, Yuka Takemura, Hiroshi Mizoguchi, Hiroshi Kuwata, Takeshi |
author_facet | Ishikawa, Takumi Takahashi, Junko Kasai, Mai Shiina, Takayuki Iijima, Yuka Takemura, Hiroshi Mizoguchi, Hiroshi Kuwata, Takeshi |
author_sort | Ishikawa, Takumi |
collection | PubMed |
description | AIMS: In Japan, cancer is the most prevalent cause of death; the number of patients suffering from cancer is increasing. Hence, there is an increased burden on pathologists to make diagnoses. To reduce pathologists’ burden, researchers have developed methods of auto-pathological diagnosis. However, virtual slides, which are created when glass slides are digitally scanned, saved in a unique format, and it is difficult for researchers to work on the virtual slides for developing their own image processing method. This paper presents the support system for pathologists and researchers who use auto-pathological diagnosis (P-SSD). Main purpose of P-SSD was to support both of pathologists and researchers. P-SSD consists of several sub-functions that make it easy not only for pathologists to screen pathological images, double-check their diagnoses, and reduce unimportant image data but also for researchers to develop and apply their original image-processing techniques to pathological images. METHODS: We originally developed P-SSD to support both pathologists and researchers developing auto-pathological diagnoses systems. Current version of P-SSD consists of five main functions as follows: (i) Loading virtual slides, (ii) making a supervised database, (iii) learning image features, (iv) detecting cancerous areas, (v) displaying results of detection. RESULTS: P-SSD reduces computer memory size random access memory utilization and the processing time required to divide the virtual slides into the smaller-size images compared with other similar software. The maximum observed reduction in computer memory size and reduction in processing time is 97% and 99.94%, respectively. CONCLUSIONS: Unlike other vendor-developed software, P-SSD has interoperability and is capable of handling virtual slides in several formats. Therefore, P-SSD can support both of pathologists and researchers, and has many potential applications in both pathological diagnosis and research area. |
format | Online Article Text |
id | pubmed-4485189 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-44851892015-07-12 Support system for pathologists and researchers Ishikawa, Takumi Takahashi, Junko Kasai, Mai Shiina, Takayuki Iijima, Yuka Takemura, Hiroshi Mizoguchi, Hiroshi Kuwata, Takeshi J Pathol Inform Original Article AIMS: In Japan, cancer is the most prevalent cause of death; the number of patients suffering from cancer is increasing. Hence, there is an increased burden on pathologists to make diagnoses. To reduce pathologists’ burden, researchers have developed methods of auto-pathological diagnosis. However, virtual slides, which are created when glass slides are digitally scanned, saved in a unique format, and it is difficult for researchers to work on the virtual slides for developing their own image processing method. This paper presents the support system for pathologists and researchers who use auto-pathological diagnosis (P-SSD). Main purpose of P-SSD was to support both of pathologists and researchers. P-SSD consists of several sub-functions that make it easy not only for pathologists to screen pathological images, double-check their diagnoses, and reduce unimportant image data but also for researchers to develop and apply their original image-processing techniques to pathological images. METHODS: We originally developed P-SSD to support both pathologists and researchers developing auto-pathological diagnoses systems. Current version of P-SSD consists of five main functions as follows: (i) Loading virtual slides, (ii) making a supervised database, (iii) learning image features, (iv) detecting cancerous areas, (v) displaying results of detection. RESULTS: P-SSD reduces computer memory size random access memory utilization and the processing time required to divide the virtual slides into the smaller-size images compared with other similar software. The maximum observed reduction in computer memory size and reduction in processing time is 97% and 99.94%, respectively. CONCLUSIONS: Unlike other vendor-developed software, P-SSD has interoperability and is capable of handling virtual slides in several formats. Therefore, P-SSD can support both of pathologists and researchers, and has many potential applications in both pathological diagnosis and research area. Medknow Publications & Media Pvt Ltd 2015-06-23 /pmc/articles/PMC4485189/ /pubmed/26167378 http://dx.doi.org/10.4103/2153-3539.158911 Text en Copyright: © 2015 Ishikawa T. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Original Article Ishikawa, Takumi Takahashi, Junko Kasai, Mai Shiina, Takayuki Iijima, Yuka Takemura, Hiroshi Mizoguchi, Hiroshi Kuwata, Takeshi Support system for pathologists and researchers |
title | Support system for pathologists and researchers |
title_full | Support system for pathologists and researchers |
title_fullStr | Support system for pathologists and researchers |
title_full_unstemmed | Support system for pathologists and researchers |
title_short | Support system for pathologists and researchers |
title_sort | support system for pathologists and researchers |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485189/ https://www.ncbi.nlm.nih.gov/pubmed/26167378 http://dx.doi.org/10.4103/2153-3539.158911 |
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