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A Herpesvirus Specific Motif of Epstein-Barr Virus DNA Polymerase Is Required for the Efficient Lytic Genome Synthesis

Epstein-Barr virus (EBV) is associated with several malignancies, including Burkitt lymphoma and nasopharyngeal carcinoma. To overcome such disorders, understanding the molecular mechanisms of the EBV replication is important. The EBV DNA polymerase (Pol) is one of the essential factors for viral ly...

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Detalles Bibliográficos
Autores principales: Narita, Yohei, Sugimoto, Atsuko, Kawashima, Daisuke, Watanabe, Takahiro, Kanda, Teru, Kimura, Hiroshi, Tsurumi, Tatsuya, Murata, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485236/
https://www.ncbi.nlm.nih.gov/pubmed/26123572
http://dx.doi.org/10.1038/srep11767