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Do Hypertension, diabetes mellitus and obesity increase the risk of severity of nephrolithiasis?

OBJECTIVE: In this study we planned to investigate the relationship between presence of kidney stones and stone burden with hypertension (HT), diabetes mellitus (DM) and body mass index (BMI). METHODS: A total of 574 patients were included in the study. None of the patients had a history of stones....

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Autores principales: Sancak, Eyup Burak, Reşorlu, Mustafa, Akbas, Alpaslan, Gulpinar, Murat Tolga, Arslan, Muhammet, Resorlu, Berkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485272/
https://www.ncbi.nlm.nih.gov/pubmed/26150845
http://dx.doi.org/10.12669/pjms.313.7086
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author Sancak, Eyup Burak
Reşorlu, Mustafa
Akbas, Alpaslan
Gulpinar, Murat Tolga
Arslan, Muhammet
Resorlu, Berkan
author_facet Sancak, Eyup Burak
Reşorlu, Mustafa
Akbas, Alpaslan
Gulpinar, Murat Tolga
Arslan, Muhammet
Resorlu, Berkan
author_sort Sancak, Eyup Burak
collection PubMed
description OBJECTIVE: In this study we planned to investigate the relationship between presence of kidney stones and stone burden with hypertension (HT), diabetes mellitus (DM) and body mass index (BMI). METHODS: A total of 574 patients were included in the study. None of the patients had a history of stones. The 121 patients with kidney stone identified on ultrasound evaluation and the 453 patients with no stones were compared in terms of HT, BMI and DM. The stone burden of 121 patients with diagnosed stones was compared in terms of the same variables. RESULTS: Of the 121 patients with kidney stones 30 (24.7%) had HT, while 66 (14.5%) of the 453 patients without stones had HT (p=0.007). BMI values of those with and without stones were 27.2 ± 4.93 kg/m(2) and 25.29 ± 4.12 kg/m(2), respectively (p<0.001). Twenty-five (20.6%) of the patients with stones diagnosed by ultrasound had DM, while 49 (10.8%) of those without stones had DM (p=0.004). When comparing patients with and without kidney stones, logistic regression analysis revealed that DM (odds ratio [OR] 2.06, 95% confidence interval [CI] 1.17 to 3.63, p=0.013) and BMI (OR 1.08, CI 1.03 to 1.13, p=0.003) were independently associated with presence of stones. No significant relationship was found between the same variables and cumulative stone diameter (CSD) and stone surface area (SA) evaluated for stone burden. CONCLUSIONS: While diabetes mellitus, Hypertension and increased Body Mass Index may add to the possibility of stone formation, they did not affect stone burden.
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spelling pubmed-44852722015-07-06 Do Hypertension, diabetes mellitus and obesity increase the risk of severity of nephrolithiasis? Sancak, Eyup Burak Reşorlu, Mustafa Akbas, Alpaslan Gulpinar, Murat Tolga Arslan, Muhammet Resorlu, Berkan Pak J Med Sci Original Article OBJECTIVE: In this study we planned to investigate the relationship between presence of kidney stones and stone burden with hypertension (HT), diabetes mellitus (DM) and body mass index (BMI). METHODS: A total of 574 patients were included in the study. None of the patients had a history of stones. The 121 patients with kidney stone identified on ultrasound evaluation and the 453 patients with no stones were compared in terms of HT, BMI and DM. The stone burden of 121 patients with diagnosed stones was compared in terms of the same variables. RESULTS: Of the 121 patients with kidney stones 30 (24.7%) had HT, while 66 (14.5%) of the 453 patients without stones had HT (p=0.007). BMI values of those with and without stones were 27.2 ± 4.93 kg/m(2) and 25.29 ± 4.12 kg/m(2), respectively (p<0.001). Twenty-five (20.6%) of the patients with stones diagnosed by ultrasound had DM, while 49 (10.8%) of those without stones had DM (p=0.004). When comparing patients with and without kidney stones, logistic regression analysis revealed that DM (odds ratio [OR] 2.06, 95% confidence interval [CI] 1.17 to 3.63, p=0.013) and BMI (OR 1.08, CI 1.03 to 1.13, p=0.003) were independently associated with presence of stones. No significant relationship was found between the same variables and cumulative stone diameter (CSD) and stone surface area (SA) evaluated for stone burden. CONCLUSIONS: While diabetes mellitus, Hypertension and increased Body Mass Index may add to the possibility of stone formation, they did not affect stone burden. Professional Medical Publications 2015 /pmc/articles/PMC4485272/ /pubmed/26150845 http://dx.doi.org/10.12669/pjms.313.7086 Text en Copyright: © Pakistan Journal of Medical Sciences http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Sancak, Eyup Burak
Reşorlu, Mustafa
Akbas, Alpaslan
Gulpinar, Murat Tolga
Arslan, Muhammet
Resorlu, Berkan
Do Hypertension, diabetes mellitus and obesity increase the risk of severity of nephrolithiasis?
title Do Hypertension, diabetes mellitus and obesity increase the risk of severity of nephrolithiasis?
title_full Do Hypertension, diabetes mellitus and obesity increase the risk of severity of nephrolithiasis?
title_fullStr Do Hypertension, diabetes mellitus and obesity increase the risk of severity of nephrolithiasis?
title_full_unstemmed Do Hypertension, diabetes mellitus and obesity increase the risk of severity of nephrolithiasis?
title_short Do Hypertension, diabetes mellitus and obesity increase the risk of severity of nephrolithiasis?
title_sort do hypertension, diabetes mellitus and obesity increase the risk of severity of nephrolithiasis?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485272/
https://www.ncbi.nlm.nih.gov/pubmed/26150845
http://dx.doi.org/10.12669/pjms.313.7086
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