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Exogenous 17-β estradiol administration blunts progression of established angiotensin II-induced abdominal aortic aneurysms in female ovariectomized mice

BACKGROUND: Abdominal aortic aneurysms (AAAs) occur predominately in males. However, AAAs in females have rapid growth rates and rupture at smaller sizes. Mechanisms contributing to AAA progression in females are undefined. We defined effects of ovariectomy, with and without 17-β estradiol (E2), on...

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Detalles Bibliográficos
Autores principales:	Thatcher, Sean E., Zhang, Xuan, Woody, Shannon, Wang, Yu, Alsiraj, Yasir, Charnigo, Richard, Daugherty, Alan, Cassis, Lisa A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485333/ https://www.ncbi.nlm.nih.gov/pubmed/26131353 http://dx.doi.org/10.1186/s13293-015-0030-1

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