Titanium Dioxide Nanoparticles Induce Endoplasmic Reticulum Stress-Mediated Autophagic Cell Death via Mitochondria-Associated Endoplasmic Reticulum Membrane Disruption in Normal Lung Cells

Nanomaterials are used in diverse fields including food, cosmetic, and medical industries. Titanium dioxide nanoparticles (TiO(2)-NP) are widely used, but their effects on biological systems and mechanism of toxicity have not been elucidated fully. Here, we report the toxicological mechanism of TiO(...

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Detalles Bibliográficos
Autores principales: Yu, Kyeong-Nam, Chang, Seung-Hee, Park, Soo Jin, Lim, Joohyun, Lee, Jinkyu, Yoon, Tae-Jong, Kim, Jun-Sung, Cho, Myung-Haing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485469/
https://www.ncbi.nlm.nih.gov/pubmed/26121477
http://dx.doi.org/10.1371/journal.pone.0131208

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