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Infiltration of Autologous Growth Factors in Chronic Tendinopathies

Achilles tendinopathy and patellar tendinopathy are among the most frequent diagnoses in sports medicine. Therapeutic treatment of the disease is difficult, particularly in chronic cases. In literature, several studies suggest the employment of Platelet-Rich Plasma as a therapeutic alternative in te...

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Autores principales: Crescibene, Antonio, Napolitano, Marcello, Sbano, Raffaella, Costabile, Enrico, Almolla, Hesham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485529/
https://www.ncbi.nlm.nih.gov/pubmed/26171277
http://dx.doi.org/10.1155/2015/924380
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author Crescibene, Antonio
Napolitano, Marcello
Sbano, Raffaella
Costabile, Enrico
Almolla, Hesham
author_facet Crescibene, Antonio
Napolitano, Marcello
Sbano, Raffaella
Costabile, Enrico
Almolla, Hesham
author_sort Crescibene, Antonio
collection PubMed
description Achilles tendinopathy and patellar tendinopathy are among the most frequent diagnoses in sports medicine. Therapeutic treatment of the disease is difficult, particularly in chronic cases. In literature, several studies suggest the employment of Platelet-Rich Plasma as a therapeutic alternative in tendinopathies. The choice of employing this method is based on the activity of growth factors contained in platelets which activate, amplify, and optimize the healing process. We selected 14 patients affected by Achilles tendinopathy and 7 patients affected by patellar tendinopathy, with a two-year final follow-up. These patients underwent a cycle of three tendinous infiltrations, after clinical and instrumental evaluation carried out by means of specific questionnaires and repeated ultrasound scans. Ultrasound scans of 18 patients showed signs of reduction in insertional irregularities. The result is confirmed by complete functional recovery of the patients, with painful symptomatology disappearing. The patients showed a clear pain reduction, along with an enhanced VISA score after the 24-month follow-up, equal to 84.2 points on a scale of 0 to 100. In conclusion, the present study provides evidence to suggest that PRP infiltration is a valid option to patients with chronic tendinopathy who did not benefit from other treatments.
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spelling pubmed-44855292015-07-13 Infiltration of Autologous Growth Factors in Chronic Tendinopathies Crescibene, Antonio Napolitano, Marcello Sbano, Raffaella Costabile, Enrico Almolla, Hesham J Blood Transfus Clinical Study Achilles tendinopathy and patellar tendinopathy are among the most frequent diagnoses in sports medicine. Therapeutic treatment of the disease is difficult, particularly in chronic cases. In literature, several studies suggest the employment of Platelet-Rich Plasma as a therapeutic alternative in tendinopathies. The choice of employing this method is based on the activity of growth factors contained in platelets which activate, amplify, and optimize the healing process. We selected 14 patients affected by Achilles tendinopathy and 7 patients affected by patellar tendinopathy, with a two-year final follow-up. These patients underwent a cycle of three tendinous infiltrations, after clinical and instrumental evaluation carried out by means of specific questionnaires and repeated ultrasound scans. Ultrasound scans of 18 patients showed signs of reduction in insertional irregularities. The result is confirmed by complete functional recovery of the patients, with painful symptomatology disappearing. The patients showed a clear pain reduction, along with an enhanced VISA score after the 24-month follow-up, equal to 84.2 points on a scale of 0 to 100. In conclusion, the present study provides evidence to suggest that PRP infiltration is a valid option to patients with chronic tendinopathy who did not benefit from other treatments. Hindawi Publishing Corporation 2015 2015-06-15 /pmc/articles/PMC4485529/ /pubmed/26171277 http://dx.doi.org/10.1155/2015/924380 Text en Copyright © 2015 Antonio Crescibene et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Crescibene, Antonio
Napolitano, Marcello
Sbano, Raffaella
Costabile, Enrico
Almolla, Hesham
Infiltration of Autologous Growth Factors in Chronic Tendinopathies
title Infiltration of Autologous Growth Factors in Chronic Tendinopathies
title_full Infiltration of Autologous Growth Factors in Chronic Tendinopathies
title_fullStr Infiltration of Autologous Growth Factors in Chronic Tendinopathies
title_full_unstemmed Infiltration of Autologous Growth Factors in Chronic Tendinopathies
title_short Infiltration of Autologous Growth Factors in Chronic Tendinopathies
title_sort infiltration of autologous growth factors in chronic tendinopathies
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485529/
https://www.ncbi.nlm.nih.gov/pubmed/26171277
http://dx.doi.org/10.1155/2015/924380
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