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Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)

Most studies on cellular senescence (CS) have been performed in vitro by employing cytotoxic agents, irradiation, chromatin and telomerase modulators or by activating certain oncogenes. All these approaches usually lead to DNA damage, gene instability and/or chromatin alterations that primarily affe...

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Detalles Bibliográficos
Autores principales:	SHILKAITIS, ANNE, GREEN, ALBERT, CHRISTOV, KONSTANTIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485653/ https://www.ncbi.nlm.nih.gov/pubmed/25997921 http://dx.doi.org/10.3892/ijo.2015.3013

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