T cell receptor-therapy in HBV-related hepatocellularcarcinoma

Adoptive transfer of lymphocytes expressing engineered T cell receptors (TCR) is a promising option for cancer treatment and could include hepatocellularcarcinoma (HCC), where therapeutic options are limited. We have recently investigated whether hepatitis B viral antigens can act as a HCC-specific...

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Detalles Bibliográficos
Autores principales: Bertoletti, Antonio, Brunetto, Maurizia, Maini, Mala K, Bonino, Ferruccio, Qasim, Waseem, Stauss, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485715/
https://www.ncbi.nlm.nih.gov/pubmed/26155416
http://dx.doi.org/10.1080/2162402X.2015.1008354
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author Bertoletti, Antonio
Brunetto, Maurizia
Maini, Mala K
Bonino, Ferruccio
Qasim, Waseem
Stauss, Hans
author_facet Bertoletti, Antonio
Brunetto, Maurizia
Maini, Mala K
Bonino, Ferruccio
Qasim, Waseem
Stauss, Hans
author_sort Bertoletti, Antonio
collection PubMed
description Adoptive transfer of lymphocytes expressing engineered T cell receptors (TCR) is a promising option for cancer treatment and could include hepatocellularcarcinoma (HCC), where therapeutic options are limited. We have recently investigated whether hepatitis B viral antigens can act as a HCC-specific antigen and thus be targeted by adoptively transferred HBV-specific TCR redirected T cells.
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spelling pubmed-44857152016-02-03 T cell receptor-therapy in HBV-related hepatocellularcarcinoma Bertoletti, Antonio Brunetto, Maurizia Maini, Mala K Bonino, Ferruccio Qasim, Waseem Stauss, Hans Oncoimmunology Author's View Adoptive transfer of lymphocytes expressing engineered T cell receptors (TCR) is a promising option for cancer treatment and could include hepatocellularcarcinoma (HCC), where therapeutic options are limited. We have recently investigated whether hepatitis B viral antigens can act as a HCC-specific antigen and thus be targeted by adoptively transferred HBV-specific TCR redirected T cells. Taylor & Francis 2015-03-19 /pmc/articles/PMC4485715/ /pubmed/26155416 http://dx.doi.org/10.1080/2162402X.2015.1008354 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Bertoletti, Antonio
Brunetto, Maurizia
Maini, Mala K
Bonino, Ferruccio
Qasim, Waseem
Stauss, Hans
T cell receptor-therapy in HBV-related hepatocellularcarcinoma
title T cell receptor-therapy in HBV-related hepatocellularcarcinoma
title_full T cell receptor-therapy in HBV-related hepatocellularcarcinoma
title_fullStr T cell receptor-therapy in HBV-related hepatocellularcarcinoma
title_full_unstemmed T cell receptor-therapy in HBV-related hepatocellularcarcinoma
title_short T cell receptor-therapy in HBV-related hepatocellularcarcinoma
title_sort t cell receptor-therapy in hbv-related hepatocellularcarcinoma
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485715/
https://www.ncbi.nlm.nih.gov/pubmed/26155416
http://dx.doi.org/10.1080/2162402X.2015.1008354
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