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Retrieval of functional TCRs from single antigen-specific T cells: Toward individualized TCR-engineered therapies
We have developed a highly versatile platform for the systematic retrieval of T-cell receptors (TCRs) from single-antigen-reactive T cells and for characterization of their function and specificity. This approach enables rapid extraction of multiple TCRs from repertoires in individuals and not only...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485745/ https://www.ncbi.nlm.nih.gov/pubmed/26140230 http://dx.doi.org/10.1080/2162402X.2015.1005523 |