Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice

Myeloid cells lacking STAT3 promote antitumor responses of NK and T cells but it is unknown if this crosstalk affects development of autochthonous tumors. We deleted STAT3 in murine myeloid cells (STAT3(Δm)) and examined the effect on the development of autochthonous colorectal cancers (CRCs). Forma...

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Detalles Bibliográficos
Autores principales: Pathria, Paulina, Gotthardt, Dagmar, Prchal-Murphy, Michaela, Putz, Eva-Maria, Holcmann, Martin, Schlederer, Michaela, Grabner, Beatrice, Crncec, Ilija, Svinka, Jasmin, Musteanu, Monica, Hoffmann, Thomas, Filipits, Martin, Berger, Walter, Poli, Valeria, Kenner, Lukas, Bilban, Martin, Casanova, Emilio, Müller, Mathias, Strobl, Birgit, Bayer, Editha, Mohr, Thomas, Sexl, Veronika, Eferl, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485776/
https://www.ncbi.nlm.nih.gov/pubmed/26137415
http://dx.doi.org/10.1080/2162402X.2014.998529

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