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Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice
Myeloid cells lacking STAT3 promote antitumor responses of NK and T cells but it is unknown if this crosstalk affects development of autochthonous tumors. We deleted STAT3 in murine myeloid cells (STAT3(Δm)) and examined the effect on the development of autochthonous colorectal cancers (CRCs). Forma...
Autores principales: | Pathria, Paulina, Gotthardt, Dagmar, Prchal-Murphy, Michaela, Putz, Eva-Maria, Holcmann, Martin, Schlederer, Michaela, Grabner, Beatrice, Crncec, Ilija, Svinka, Jasmin, Musteanu, Monica, Hoffmann, Thomas, Filipits, Martin, Berger, Walter, Poli, Valeria, Kenner, Lukas, Bilban, Martin, Casanova, Emilio, Müller, Mathias, Strobl, Birgit, Bayer, Editha, Mohr, Thomas, Sexl, Veronika, Eferl, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485776/ https://www.ncbi.nlm.nih.gov/pubmed/26137415 http://dx.doi.org/10.1080/2162402X.2014.998529 |
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