Modifications of the mouse bone marrow microenvironment favor angiogenesis and correlate with disease progression from asymptomatic to symptomatic multiple myeloma

While multiple myeloma (MM) is almost invariably preceded by asymptomatic monoclonal gammopathy of undetermined significance (MGUS) and/or smoldering MM (SMM), the alterations of the bone marrow (BM) microenvironment that establish progression to symptomatic disease are circumstantial. Here we show...

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Detalles Bibliográficos
Autores principales: Calcinotto, Arianna, Ponzoni, Maurilio, Ria, Roberto, Grioni, Matteo, Cattaneo, Elena, Villa, Isabella, Sabrina Bertilaccio, Maria Teresa, Chesi, Marta, Rubinacci, Alessandro, Tonon, Giovanni, Bergsagel, P Leif, Vacca, Angelo, Bellone, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485787/
https://www.ncbi.nlm.nih.gov/pubmed/26155424
http://dx.doi.org/10.1080/2162402X.2015.1008850

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