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New role for antigen-presenting activated pDCs in promoting Th17 cells and impacting antitumor immunity
Plasmacytoid dendritic cells (pDCs) are not only potent inflammatory cytokine producers but also function as antigen-presenting cells (APCs). We have shown that vaccination using CpG-B activated tumor antigen (Ag) presenting pDCs induce Th17 cells that promote intratumoral immune cell recruitment, i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485838/ https://www.ncbi.nlm.nih.gov/pubmed/26155409 http://dx.doi.org/10.4161/2162402X.2014.988476 |