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Profile of blinatumomab and its potential in the treatment of relapsed/refractory acute lymphoblastic leukemia
The CD19 marker is expressed on the surface of normal and malignant immature or mature B-cells. On the other hand, immunotherapy involving T-cells is a promising modality of treatment for many neoplastic diseases including leukemias and lymphomas. The CD19/CD3-bispecific T-cell-engaging (BiTE(®)) mo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485855/ https://www.ncbi.nlm.nih.gov/pubmed/26170691 http://dx.doi.org/10.2147/OTT.S70524 |