Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APC(Min/+) Mice

Mutation of the adenomatous polyposis coli (APC gene), an early event in the adenoma-carcinoma sequence, is present in 70-80% of sporadic human colorectal adenomas and carcinomas. To test the hypothesis that mutation of the APC gene alters microbial interactions with host intestinal mucosa prior to...

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Detalles Bibliográficos
Autores principales: Son, Joshua S., Khair, Shanawaj, Pettet, Donald W., Ouyang, Nengtai, Tian, Xinyu, Zhang, Yuanhao, Zhu, Wei, Mackenzie, Gerardo G., Robertson, Charles E., Ir, Diana, Frank, Daniel N., Rigas, Basil, Li, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485894/
https://www.ncbi.nlm.nih.gov/pubmed/26121046
http://dx.doi.org/10.1371/journal.pone.0127985

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