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P16 Methylation as an Early Predictor for Cancer Development From Oral Epithelial Dysplasia: A Double-blind Multicentre Prospective Study

BACKGROUND: Silencing of P16 through methylation and locus deletion is the most frequent early events in carcinogenesis. The aim of this study is to prospectively determine if early P16 methylation is a predictor for oral cancer development. METHODS: Patients (n = 181) with mild or moderate oral epi...

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Detalles Bibliográficos
Autores principales:	Liu, Hongwei, Liu, Xue-wei, Dong, Guangying, Zhou, Jing, Liu, Yang, Gao, Yan, Liu, Xiao-yong, Gu, Liankun, Sun, Zheng, Deng, Dajun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485905/ https://www.ncbi.nlm.nih.gov/pubmed/26137587 http://dx.doi.org/10.1016/j.ebiom.2015.03.015

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