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Elevated Urinary Connective Tissue Growth Factor in Diabetic Nephropathy Is Caused by Local Production and Tubular Dysfunction

Connective tissue growth factor (CTGF; CCN2) plays a role in the development of diabetic nephropathy (DN). Urinary CTGF (uCTGF) is elevated in DN patients and has been proposed as a biomarker for disease progression, but it is unknown which pathophysiological factors contribute to elevated uCTGF. We...

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Detalles Bibliográficos
Autores principales:	Gerritsen, Karin G. F., Leeuwis, Jan Willem, Koeners, Maarten P., Bakker, Stephan J. L., van Oeveren, Willem, Aten, Jan, Tarnow, Lise, Rossing, Peter, Wetzels, Jack F. M., Joles, Jaap A., Kok, Robbert Jan, Goldschmeding, Roel, Nguyen, Tri Q.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485941/ https://www.ncbi.nlm.nih.gov/pubmed/26171399 http://dx.doi.org/10.1155/2015/539787

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