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Usage of Probabilistic and General Regression Neural Network for Early Detection and Prevention of Oral Cancer

In India, the oral cancers are usually presented in advanced stage of malignancy. It is critical to ascertain the diagnosis in order to initiate most advantageous treatment of the suspicious lesions. The main hurdle in appropriate treatment and control of oral cancer is identification and risk asses...

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Autores principales: Sharma, Neha, Om, Hari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485993/
https://www.ncbi.nlm.nih.gov/pubmed/26171415
http://dx.doi.org/10.1155/2015/234191
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author Sharma, Neha
Om, Hari
author_facet Sharma, Neha
Om, Hari
author_sort Sharma, Neha
collection PubMed
description In India, the oral cancers are usually presented in advanced stage of malignancy. It is critical to ascertain the diagnosis in order to initiate most advantageous treatment of the suspicious lesions. The main hurdle in appropriate treatment and control of oral cancer is identification and risk assessment of early disease in the community in a cost-effective fashion. The objective of this research is to design a data mining model using probabilistic neural network and general regression neural network (PNN/GRNN) for early detection and prevention of oral malignancy. The model is built using the oral cancer database which has 35 attributes and 1025 records. All the attributes pertaining to clinical symptoms and history are considered to classify malignant and non-malignant cases. Subsequently, the model attempts to predict particular type of cancer, its stage and extent with the help of attributes pertaining to symptoms, gross examination and investigations. Also, the model envisages anticipating the survivability of a patient on the basis of treatment and follow-up details. Finally, the performance of the PNN/GRNN model is compared with that of other classification models. The classification accuracy of PNN/GRNN model is 80% and hence is better for early detection and prevention of the oral cancer.
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spelling pubmed-44859932015-07-13 Usage of Probabilistic and General Regression Neural Network for Early Detection and Prevention of Oral Cancer Sharma, Neha Om, Hari ScientificWorldJournal Research Article In India, the oral cancers are usually presented in advanced stage of malignancy. It is critical to ascertain the diagnosis in order to initiate most advantageous treatment of the suspicious lesions. The main hurdle in appropriate treatment and control of oral cancer is identification and risk assessment of early disease in the community in a cost-effective fashion. The objective of this research is to design a data mining model using probabilistic neural network and general regression neural network (PNN/GRNN) for early detection and prevention of oral malignancy. The model is built using the oral cancer database which has 35 attributes and 1025 records. All the attributes pertaining to clinical symptoms and history are considered to classify malignant and non-malignant cases. Subsequently, the model attempts to predict particular type of cancer, its stage and extent with the help of attributes pertaining to symptoms, gross examination and investigations. Also, the model envisages anticipating the survivability of a patient on the basis of treatment and follow-up details. Finally, the performance of the PNN/GRNN model is compared with that of other classification models. The classification accuracy of PNN/GRNN model is 80% and hence is better for early detection and prevention of the oral cancer. Hindawi Publishing Corporation 2015 2015-06-15 /pmc/articles/PMC4485993/ /pubmed/26171415 http://dx.doi.org/10.1155/2015/234191 Text en Copyright © 2015 N. Sharma and H. Om. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sharma, Neha
Om, Hari
Usage of Probabilistic and General Regression Neural Network for Early Detection and Prevention of Oral Cancer
title Usage of Probabilistic and General Regression Neural Network for Early Detection and Prevention of Oral Cancer
title_full Usage of Probabilistic and General Regression Neural Network for Early Detection and Prevention of Oral Cancer
title_fullStr Usage of Probabilistic and General Regression Neural Network for Early Detection and Prevention of Oral Cancer
title_full_unstemmed Usage of Probabilistic and General Regression Neural Network for Early Detection and Prevention of Oral Cancer
title_short Usage of Probabilistic and General Regression Neural Network for Early Detection and Prevention of Oral Cancer
title_sort usage of probabilistic and general regression neural network for early detection and prevention of oral cancer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485993/
https://www.ncbi.nlm.nih.gov/pubmed/26171415
http://dx.doi.org/10.1155/2015/234191
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