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Epigenetics of Notch1 regulation in pulmonary microvascular rarefaction following extrauterine growth restriction
BACKGROUND: Extrauterine growth restriction (EUGR) plays an important role in the developmental origin of adult cardiovascular diseases. In an EUGR rat model, we reported an elevated pulmonary arterial pressure in adults and genome-wide epigenetic modifications in pulmonary vascular endothelial cell...
Autores principales: | Tang, Li-Li, Zhang, Li-Yan, Lao, Lin-Jiang, Hu, Qiong-Yao, Gu, Wei-Zhong, Fu, Lin-Chen, Du, Li-Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486133/ https://www.ncbi.nlm.nih.gov/pubmed/26040933 http://dx.doi.org/10.1186/s12931-015-0226-2 |
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