Cargando…
Inflammation-regulating factors in ascites as predictive biomarkers of drug resistance and progression-free survival in serous epithelial ovarian cancers
BACKGROUND: Platinum-based combination therapy is the standard first-line treatment for women with advanced serous epithelial ovarian carcinoma (EOC). However, about 20 % will not respond and are considered clinically resistant. The availability of biomarkers to predict responses to the initial ther...
Autores principales: | Lane, Denis, Matte, Isabelle, Garde-Granger, Perrine, Laplante, Claude, Carignan, Alex, Rancourt, Claudine, Piché, Alain |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486134/ https://www.ncbi.nlm.nih.gov/pubmed/26122176 http://dx.doi.org/10.1186/s12885-015-1511-7 |
Ejemplares similares
-
CCL18 from ascites promotes ovarian cancer cell migration through proline-rich tyrosine kinase 2 signaling
por: Lane, Denis, et al.
Publicado: (2016) -
Osteoprotegerin (OPG) activates integrin, focal adhesion kinase (FAK), and Akt signaling in ovarian cancer cells to attenuate TRAIL-induced apoptosis
por: Lane, Denis, et al.
Publicado: (2013) -
The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer
por: Lane, Denis, et al.
Publicado: (2010) -
Prognostic significance of IL-6 and IL-8 ascites levels in ovarian cancer patients
por: Lane, Denis, et al.
Publicado: (2011) -
Osteoprotegerin (OPG) protects ovarian cancer cells from TRAIL-induced apoptosis but does not contribute to malignant ascites-mediated attenuation of TRAIL-induced apoptosis
por: Lane, Denis, et al.
Publicado: (2012)