Down-regulation of the autophagy gene, ATG7, protects bone marrow-derived mesenchymal stem cells from stressful conditions

BACKGROUND: Mesenchymal stem cells (MSCs) are valuable for cell-based therapy. However, their application is limited owing to their low survival rate when exposed to stressful conditions. Autophagy, the process by which cells recycle the cytoplasm and dispose of defective organelles, is activated by...

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Detalles Bibliográficos
Autores principales: Molaei, Sedigheh, Roudkenar, Mehryar Habibi, Amiri, Fatemeh, Harati, Mozhgan Dehghan, Bahadori, Marzie, Jaleh, Fatemeh, Jalili, Mohammad Ali, Mohammadi Roushandeh, Amaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486163/
https://www.ncbi.nlm.nih.gov/pubmed/26157777
http://dx.doi.org/10.5045/br.2015.50.2.80

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