Pancreatic mucinous cystic neoplasm in a transgender patient

BACKGROUND: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. CASE PRESENTATION: Here, we present the case of a 31-year-old surg...

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Detalles Bibliográficos
Autores principales: Foster, Deshka, Shaikh, Mohammad F., Gleeson, Elizabeth, Babcock, Blake D., Lin, Jianping, Ownbey, Robert T., Hysell, Mark E., Ringold, Daniel, Bowne, Wilbur B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486435/
https://www.ncbi.nlm.nih.gov/pubmed/26104783
http://dx.doi.org/10.1186/s12957-015-0620-8
Descripción
Sumario:BACKGROUND: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. CASE PRESENTATION: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. CONCLUSION: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient’s neoplasm.

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