Pancreatic mucinous cystic neoplasm in a transgender patient

BACKGROUND: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. CASE PRESENTATION: Here, we present the case of a 31-year-old surg...

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Autores principales: Foster, Deshka, Shaikh, Mohammad F., Gleeson, Elizabeth, Babcock, Blake D., Lin, Jianping, Ownbey, Robert T., Hysell, Mark E., Ringold, Daniel, Bowne, Wilbur B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486435/
https://www.ncbi.nlm.nih.gov/pubmed/26104783
http://dx.doi.org/10.1186/s12957-015-0620-8
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author Foster, Deshka
Shaikh, Mohammad F.
Gleeson, Elizabeth
Babcock, Blake D.
Lin, Jianping
Ownbey, Robert T.
Hysell, Mark E.
Ringold, Daniel
Bowne, Wilbur B.
author_facet Foster, Deshka
Shaikh, Mohammad F.
Gleeson, Elizabeth
Babcock, Blake D.
Lin, Jianping
Ownbey, Robert T.
Hysell, Mark E.
Ringold, Daniel
Bowne, Wilbur B.
author_sort Foster, Deshka
collection PubMed
description BACKGROUND: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. CASE PRESENTATION: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. CONCLUSION: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient’s neoplasm.
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spelling pubmed-44864352015-07-02 Pancreatic mucinous cystic neoplasm in a transgender patient Foster, Deshka Shaikh, Mohammad F. Gleeson, Elizabeth Babcock, Blake D. Lin, Jianping Ownbey, Robert T. Hysell, Mark E. Ringold, Daniel Bowne, Wilbur B. World J Surg Oncol Case Report BACKGROUND: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. CASE PRESENTATION: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. CONCLUSION: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient’s neoplasm. BioMed Central 2015-06-24 /pmc/articles/PMC4486435/ /pubmed/26104783 http://dx.doi.org/10.1186/s12957-015-0620-8 Text en © Foster et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Foster, Deshka
Shaikh, Mohammad F.
Gleeson, Elizabeth
Babcock, Blake D.
Lin, Jianping
Ownbey, Robert T.
Hysell, Mark E.
Ringold, Daniel
Bowne, Wilbur B.
Pancreatic mucinous cystic neoplasm in a transgender patient
title Pancreatic mucinous cystic neoplasm in a transgender patient
title_full Pancreatic mucinous cystic neoplasm in a transgender patient
title_fullStr Pancreatic mucinous cystic neoplasm in a transgender patient
title_full_unstemmed Pancreatic mucinous cystic neoplasm in a transgender patient
title_short Pancreatic mucinous cystic neoplasm in a transgender patient
title_sort pancreatic mucinous cystic neoplasm in a transgender patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486435/
https://www.ncbi.nlm.nih.gov/pubmed/26104783
http://dx.doi.org/10.1186/s12957-015-0620-8
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AT ownbeyrobertt pancreaticmucinouscysticneoplasminatransgenderpatient
AT hysellmarke pancreaticmucinouscysticneoplasminatransgenderpatient
AT ringolddaniel pancreaticmucinouscysticneoplasminatransgenderpatient
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