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High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is not a single uniform disease. It consists of several subgroups with different cytogenetic and molecular genetic aberrations, clinical presentations and outcomes. Banding cytogenetics plays a pivotal role in the detection of recurrent chromosomal rear...

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Detalles Bibliográficos
Autores principales: Othman, Moneeb A. K., Melo, Joana B., Carreira, Isabel M., Rincic, Martina, Glaser, Anita, Grygalewicz, Beata, Gruhn, Bernd, Wilhelm, Kathleen, Rittscher, Katharina, Meyer, Britta, Silva, Maria Luiza Macedo, de Jesus Marques Salles, Terezinha, Liehr, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486437/
https://www.ncbi.nlm.nih.gov/pubmed/26136832
http://dx.doi.org/10.1186/s13039-015-0153-4