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Comparative analyses of downstream signal transduction targets modulated after activation of the AT(1) receptor by two β-arrestin-biased agonists

G protein-coupled receptors (GPCRs) are involved in essentially all physiological processes in mammals. The classical GPCR signal transduction mechanism occurs by coupling to G protein, but it has recently been demonstrated that interaction with β-arrestins leads to activation of pathways that are i...

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Detalles Bibliográficos
Autores principales:	Santos, Geisa A., Duarte, Diego A., Parreiras-e-Silva, Lucas T., Teixeira, Felipe R., Silva-Rocha, Rafael, Oliveira, Eduardo B., Bouvier, Michel, Costa-Neto, Claudio M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486767/ https://www.ncbi.nlm.nih.gov/pubmed/26191004 http://dx.doi.org/10.3389/fphar.2015.00131

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