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Native Promoter Strategy for High-Yielding Synthesis and Engineering of Fungal Secondary Metabolites
[Image: see text] Strategies are needed for the robust production of cryptic, silenced, or engineered secondary metabolites in fungi. The filamentous fungus Fusarium heterosporum natively synthesizes the polyketide equisetin at >2 g L(–1) in a controllable manner. We hypothesized that this produc...
Autores principales: | Kakule, Thomas B., Jadulco, Raquel C., Koch, Michael, Janso, Jeffrey E., Barrows, Louis R., Schmidt, Eric W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487227/ https://www.ncbi.nlm.nih.gov/pubmed/25226362 http://dx.doi.org/10.1021/sb500296p |
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