Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir

The fixed-dose combination of Efavirenz/Emtricitabine/Tenofovir is a first-line agent for the treatment of HIV; however few cases have reported hepatotoxicity associated with the drug. We report a case of Efavirenz/Emtricitabine/Tenofovir-associated hepatotoxicity presenting mainly with hepatocellul...

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Autores principales: Patil, Rashmee, Ona, Mel A., Papafragkakis, Haris, Carey, Jeanne, Moshenyat, Yitzchak, Alhaddad, Adib, Anand, Sury
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487274/
https://www.ncbi.nlm.nih.gov/pubmed/26161275
http://dx.doi.org/10.1155/2015/280353
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author Patil, Rashmee
Ona, Mel A.
Papafragkakis, Haris
Carey, Jeanne
Moshenyat, Yitzchak
Alhaddad, Adib
Anand, Sury
author_facet Patil, Rashmee
Ona, Mel A.
Papafragkakis, Haris
Carey, Jeanne
Moshenyat, Yitzchak
Alhaddad, Adib
Anand, Sury
author_sort Patil, Rashmee
collection PubMed
description The fixed-dose combination of Efavirenz/Emtricitabine/Tenofovir is a first-line agent for the treatment of HIV; however few cases have reported hepatotoxicity associated with the drug. We report a case of Efavirenz/Emtricitabine/Tenofovir-associated hepatotoxicity presenting mainly with hepatocellular injury characterized by extremely elevated aminotransferase levels, which resolved without acute liver failure or need for liver transplant referral.
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spelling pubmed-44872742015-07-09 Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir Patil, Rashmee Ona, Mel A. Papafragkakis, Haris Carey, Jeanne Moshenyat, Yitzchak Alhaddad, Adib Anand, Sury Case Reports Hepatol Case Report The fixed-dose combination of Efavirenz/Emtricitabine/Tenofovir is a first-line agent for the treatment of HIV; however few cases have reported hepatotoxicity associated with the drug. We report a case of Efavirenz/Emtricitabine/Tenofovir-associated hepatotoxicity presenting mainly with hepatocellular injury characterized by extremely elevated aminotransferase levels, which resolved without acute liver failure or need for liver transplant referral. Hindawi Publishing Corporation 2015 2015-06-16 /pmc/articles/PMC4487274/ /pubmed/26161275 http://dx.doi.org/10.1155/2015/280353 Text en Copyright © 2015 Rashmee Patil et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Patil, Rashmee
Ona, Mel A.
Papafragkakis, Haris
Carey, Jeanne
Moshenyat, Yitzchak
Alhaddad, Adib
Anand, Sury
Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir
title Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir
title_full Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir
title_fullStr Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir
title_full_unstemmed Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir
title_short Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir
title_sort acute liver toxicity due to efavirenz/emtricitabine/tenofovir
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487274/
https://www.ncbi.nlm.nih.gov/pubmed/26161275
http://dx.doi.org/10.1155/2015/280353
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