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Application of CRISPR/Cas9 for biomedical discoveries

The Clustered Regions of Interspersed Palindromic Repeats-Cas9 (CRISPR/Cas9), a viral defense system found in bacteria and archaea, has emerged as a tour de force genome editing tool. The CRISPR/Cas9 system is much easier to customize and optimize because the site selection for DNA cleavage is guide...

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Detalles Bibliográficos
Autores principales: Riordan, Sean M., Heruth, Daniel P., Zhang, Li Q., Ye, Shui Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487574/
https://www.ncbi.nlm.nih.gov/pubmed/26137216
http://dx.doi.org/10.1186/s13578-015-0027-9