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Application of CRISPR/Cas9 for biomedical discoveries

The Clustered Regions of Interspersed Palindromic Repeats-Cas9 (CRISPR/Cas9), a viral defense system found in bacteria and archaea, has emerged as a tour de force genome editing tool. The CRISPR/Cas9 system is much easier to customize and optimize because the site selection for DNA cleavage is guide...

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Detalles Bibliográficos
Autores principales:	Riordan, Sean M., Heruth, Daniel P., Zhang, Li Q., Ye, Shui Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487574/ https://www.ncbi.nlm.nih.gov/pubmed/26137216 http://dx.doi.org/10.1186/s13578-015-0027-9

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