Cargando…

Rearrangement of chromosome bands 12q14~15 causing HMGA2-SOX5 gene fusion and HMGA2 expression in extraskeletal osteochondroma

We describe two cases of extraskeletal osteochon-droma in which chromosome bands 12q14~15 were visibly rearranged through a pericentric inv(12). Molecular analysis of the first tumor showed that both transcript 1 (NM_003483) and transcript 2 (NM_003484) of HMGA2 were expressed. In the second tumor,...

Descripción completa

Detalles Bibliográficos
Autores principales:	PANAGOPOULOS, IOANNIS, BJERKEHAGEN, BODIL, GORUNOVA, LUDMILA, TAKSDAL, INGEBORG, HEIM, SVERRE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487666/ https://www.ncbi.nlm.nih.gov/pubmed/26043835 http://dx.doi.org/10.3892/or.2015.4035

Ejemplares similares

The recurrent chromosomal translocation t(12;18) (q14~15;q12~21) causes the fusion gene HMGA2-SETBP1 and HMGA2 expression in lipoma and osteochondrolipoma
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2015)

Fusion of the HMGA2 and C9orf92 genes in myolipoma with t(9;12)(p22;q14)
por: Panagopoulos, Ioannis, et al.
Publicado: (2016)

Fusion of the TBL1XR1 and HMGA1 genes in splenic hemangioma with t(3;6)(q26;p21)
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2015)

Molecular characterization of the t(4;12)(q27~28;q14~15) chromosomal rearrangement in lipoma
por: Agostini, Antonio, et al.
Publicado: (2016)

Fusion of the Genes EWSR1 and PBX3 in Retroperitoneal Leiomyoma with t(9;22)(q33;q12)
por: Panagopoulos, Ioannis, et al.
Publicado: (2015)

Novel KAT6B-KANSL1 Fusion Gene Identified by RNA Sequencing in Retroperitoneal Leiomyoma with t(10;17)(q22;q21)
por: Panagopoulos, Ioannis, et al.
Publicado: (2015)

The “Grep” Command But Not FusionMap, FusionFinder or ChimeraScan Captures the CIC-DUX4 Fusion Gene from Whole Transcriptome Sequencing Data on a Small Round Cell Tumor with t(4;19)(q35;q13)
por: Panagopoulos, Ioannis, et al.
Publicado: (2014)

Identification of SETD2-NF1 fusion gene in a pediatric spindle cell tumor with the chromosomal translocation t(3;17)(p21;q12)
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2014)

Several fusion genes identified by whole transcriptome sequencing in a spindle cell sarcoma with rearrangements of chromosome arm 12q and MDM2 amplification
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2014)

Novel CSF1-S100A10 fusion gene and CSF1 transcript identified by RNA sequencing in tenosynovial giant cell tumors
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2014)

Karyotyping and analysis of GNAS locus in intramuscular myxomas
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

HMGA2 expression pattern and TERT mutations in tumors of the vulva
por: AGOSTINI, ANTONIO, et al.
Publicado: (2015)

Loss of chromosome 13 material in cellular angiofibromas indicates pathogenetic similarity with spindle cell lipomas
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Gene fusions AHRR-NCOA2, NCOA2-ETV4, ETV4-AHRR, P4HA2-TBCK, and TBCK-P4HA2 resulting from the translocations t(5;8;17)(p15;q13;q21) and t(4;5)(q24;q31) in a soft tissue angiofibroma
por: Panagopoulos, Ioannis, et al.
Publicado: (2016)

Novel Fusion of MYST/Esa1-Associated Factor 6 and PHF1 in Endometrial Stromal Sarcoma
por: Panagopoulos, Ioannis, et al.
Publicado: (2012)

Genetic heterogeneity in leiomyomas of deep soft tissue
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Expressions of miR-30c and let-7a are inversely correlated with HMGA2 expression in squamous cell carcinoma of the vulva
por: Agostini, Antonio, et al.
Publicado: (2016)

Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression
por: Agostini, Antonio, et al.
Publicado: (2017)

Assessment of HMGA2 and PLAG1 rearrangements in breast adenomyoepitheliomas
por: Pareja, Fresia, et al.
Publicado: (2019)

Extraskeletal osteochondroma of the buttock.
por: Lim, Sung-Chul, et al.
Publicado: (2003)

Novel ZEB2-BCL11B Fusion Gene Identified by RNA-Sequencing in Acute Myeloid Leukemia with t(2;14)(q22;q32)
por: Torkildsen, Synne, et al.
Publicado: (2015)

Whole-Transcriptome Sequencing Identifies Novel IRF2BP2-CDX1 Fusion Gene Brought about by Translocation t(1;5)(q42;q32) in Mesenchymal Chondrosarcoma
por: Nyquist, Kaja B., et al.
Publicado: (2012)

RNA‐sequencing identifies novel GREB1‐NCOA2 fusion gene in a uterine sarcoma with the chromosomal translocation t(2;8)(p25;q13)
por: Brunetti, Marta, et al.
Publicado: (2017)

Expression levels of HMGA2 in adipocytic tumors correlate with morphologic and cytogenetic subgroups
por: Bartuma, Hammurabi, et al.
Publicado: (2009)

HMGA1 and HMGA2 expression and comparative analyses of HMGA2, Lin28 and let-7 miRNAs in oral squamous cell carcinoma
por: Sterenczak, Katharina Anna, et al.
Publicado: (2014)

Myeloid leukemia with t(7;21)(p22;q22) and 5q deletion
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2013)

FAM53B truncation caused by t(10;19)(q26;q13) chromosome translocation in acute lymphoblastic leukemia
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3′UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2
por: Wang, Yuan, et al.
Publicado: (2017)

Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity
por: Gorunova, Ludmila, et al.
Publicado: (2022)

Hmga1/Hmga2 double knock-out mice display a “superpygmy” phenotype
por: Federico, Antonella, et al.
Publicado: (2014)

Identification of an EPC2-PHF1 fusion transcript in low-grade endometrial stromal sarcoma
por: Brunetti, Marta, et al.
Publicado: (2018)

Extraskeletal Osteochondroma Arising on the Plantar Region
por: Ueno, Takashi, et al.
Publicado: (2011)

Fusion of the genes ataxin 2 like, ATXN2L, and Janus kinase 2, JAK2, in cutaneous CD4 positive T-cell lymphoma
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Cryptic FUS-ERG fusion identified by RNA-sequencing in childhood acute myeloid leukemia
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2013)

3′RNA and whole‐genome sequencing of archival uterine leiomyomas reveal a tumor subtype with chromosomal rearrangements affecting either HMGA2, HMGA1, or PLAG1
por: Jokinen, Vilja, et al.
Publicado: (2022)

RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
por: Panagopoulos, Ioannis, et al.
Publicado: (2016)

RUNX1-PDCD6 fusion resulting from a novel t(5;21)(p15;q22) chromosome translocation in myelodysplastic syndrome secondary to chronic lymphocytic leukemia
por: Panagopoulos, Ioannis, et al.
Publicado: (2018)

Hmga2 translocation induced in skin tumorigenesis
por: Li, Yong, et al.
Publicado: (2017)

Emerging roles for HMGA2 in colorectal cancer
por: Wang, Xin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tsl4pqugprfm4f1tnb8nl31mns