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Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer’s disease patients and healthy controls
INTRODUCTION: Synaptic dysfunction and degeneration are central events in Alzheimer’s disease (AD) pathophysiology that are thought to occur early in disease progression. Synaptic pathology may be studied by examining protein biomarkers specific for different synaptic elements. We recently showed th...
Autores principales: | Kvartsberg, Hlin, Portelius, Erik, Andreasson, Ulf, Brinkmalm, Gunnar, Hellwig, Konstantin, Lelental, Natalia, Kornhuber, Johannes, Hansson, Oskar, Minthon, Lennart, Spitzer, Philipp, Maler, Juan M, Zetterberg, Henrik, Blennow, Kaj, Lewczuk, Piotr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487851/ https://www.ncbi.nlm.nih.gov/pubmed/26136856 http://dx.doi.org/10.1186/s13195-015-0124-3 |
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