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Role of Bone Marrow-Derived Stem Cells in Polyps Development in Mice with Apc(Min/+) Mutation

We explored the hypothesis that an altered microenvironment (intestinal adenomatous polyp) could modify the differentiation program of bone marrow-derived stem cells (BMSCs), involving them in colon carcinogenesis. Sublethally irradiated 8-week-old female Apc(Min/+) mice were transplanted with bone...

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Detalles Bibliográficos
Autores principales: Barone, Michele, Scavo, Maria Principia, Licinio, Raffaele, Piombino, Michele, De Tullio, Nicola, Mallamaci, Rosanna, Di Leo, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488009/
https://www.ncbi.nlm.nih.gov/pubmed/26167184
http://dx.doi.org/10.1155/2015/354193

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