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Sugar Derivatives of Morphine: A New Window for the Development of Potent Anesthetic Drugs

This review provides a short account of carbohydrate derivatives of an important natural drug, morphine, along with their comparative efficacies as anesthetic agent. Sugar derivatives are found to have more prospect as anesthetic drug than morphine itself owing to their enhanced bioavailability. Syn...

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Detalles Bibliográficos
Autores principales: Jash, Shyamal K., Gorai, Dilip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488153/
https://www.ncbi.nlm.nih.gov/pubmed/25997823
http://dx.doi.org/10.1007/s13659-015-0060-8
Descripción
Sumario:This review provides a short account of carbohydrate derivatives of an important natural drug, morphine, along with their comparative efficacies as anesthetic agent. Sugar derivatives are found to have more prospect as anesthetic drug than morphine itself owing to their enhanced bioavailability. Synthetic schemes of these sugar derivatives and information on related patents are also included in this manuscript.