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Dissolution of Commercially Available Mesalamine Formulations at Various pH Levels

INTRODUCTION: Mesalamine (5-aminosalicylic acid; 5-ASA) is recommended first-line therapy for mild-to-moderate ulcerative colitis. Many mesalamine formulations employ a pH-dependent release mechanism designed to maximize drug release in the colon. This study compared the in vitro release of 5-ASA fr...

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Detalles Bibliográficos
Autor principal: Tenjarla, Srini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488180/
https://www.ncbi.nlm.nih.gov/pubmed/26115756
http://dx.doi.org/10.1007/s40268-015-0097-5