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Dissolution of Commercially Available Mesalamine Formulations at Various pH Levels
INTRODUCTION: Mesalamine (5-aminosalicylic acid; 5-ASA) is recommended first-line therapy for mild-to-moderate ulcerative colitis. Many mesalamine formulations employ a pH-dependent release mechanism designed to maximize drug release in the colon. This study compared the in vitro release of 5-ASA fr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488180/ https://www.ncbi.nlm.nih.gov/pubmed/26115756 http://dx.doi.org/10.1007/s40268-015-0097-5 |