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Clinical Significance of MLH1 Methylation and CpG Island Methylator Phenotype as Prognostic Markers in Patients with Gastric Cancer
BACKGROUND: To improve the outcome of patients suffering from gastric cancer, a better understanding of underlying genetic and epigenetic events in this malignancy is required. Although CpG island methylator phenotype (CIMP) and microsatellite instability (MSI) have been shown to play pivotal roles...
Autores principales: | Shigeyasu, Kunitoshi, Nagasaka, Takeshi, Mori, Yoshiko, Yokomichi, Naosuke, Kawai, Takashi, Fuji, Tomokazu, Kimura, Keisuke, Umeda, Yuzo, Kagawa, Shunsuke, Goel, Ajay, Fujiwara, Toshiyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488282/ https://www.ncbi.nlm.nih.gov/pubmed/26121593 http://dx.doi.org/10.1371/journal.pone.0130409 |
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