Independent Neuronal Origin of Seizures and Behavioral Comorbidities in an Animal Model of a Severe Childhood Genetic Epileptic Encephalopathy

The childhood epileptic encephalopathies (EE’s) are seizure disorders that broadly impact development including cognitive, sensory and motor progress with severe consequences and comorbidities. Recently, mutations in DNM1 (dynamin 1) have been implicated in two EE syndromes, Lennox-Gastaut Syndrome...

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Detalles Bibliográficos
Autores principales: Asinof, Samuel K., Sukoff Rizzo, Stacey J., Buckley, Alexandra R., Beyer, Barbara J., Letts, Verity A., Frankel, Wayne N., Boumil, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488318/
https://www.ncbi.nlm.nih.gov/pubmed/26125563
http://dx.doi.org/10.1371/journal.pgen.1005347

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