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Hippo Stabilises Its Adaptor Salvador by Antagonising the HECT Ubiquitin Ligase Herc4

Signalling through the Hippo (Hpo) pathway involves a kinase cascade, which leads to the phosphorylation and inactivation of the pro-growth transcriptional co-activator Yorkie (Yki). Despite the identification of a large number of pathway members and modulators, our understanding of the molecular ev...

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Detalles Bibliográficos
Autores principales: Aerne, Birgit L., Gailite, Ieva, Sims, David, Tapon, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488328/
https://www.ncbi.nlm.nih.gov/pubmed/26125558
http://dx.doi.org/10.1371/journal.pone.0131113